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5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione → 1-(Cyclobutyl)methyl-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione | HCID 10493727 | — |
| 反応物 | Cyclobutylmethyl 4-methylbenzenesulfonate | HCID 13163931 | — |
| 生成物 | 1-(Cyclobutyl)methyl-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione | HCID 15957702 | 41% |
反応手順
5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and (cyclobutyl)methyl para-toluenesulfonate were reacted by the same way with the example 1 to obtain the titled compound (147 mg, yield: 41.0%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06987114B1 |
| 出典データセット | uspto-grants-2006_01 |
| ORD ID | ord-9fa75aaa0402485fafc70c9260c76daf |
| 出典メモ | uspto-grants-2006_01 |