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5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione → 1-(Cyclobutylmethyl)-6-(3,5-dimethylphenoxy)-5-ethyl-pyrimidine-2,4-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione | HCID 10923266 | — |
| 反応物 | Cyclobutylmethyl 4-methylbenzenesulfonate | HCID 13163931 | — |
| 生成物 | 1-(Cyclobutylmethyl)-6-(3,5-dimethylphenoxy)-5-ethyl-pyrimidine-2,4-dione | HCID 9949342 | 58.5% |
反応手順
5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and (cyclobutyl)methyl para-toluenesulfonate were reacted by the same way with the example 1 to obtain the titled compound (192 mg, yield: 58.5%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06987114B1 |
| 出典データセット | uspto-grants-2006_01 |
| ORD ID | ord-9db64a969c444453be515a0d74a73ce1 |
| 出典メモ | uspto-grants-2006_01 |