化工社化工社 化学情報印刷レポート · 研究参考用
3,5-Difluorobenzyl bromide → 1-[(3,5-Difluorophenyl)methyl]-6-(3,5-dimethylbenzoyl)-5-isopropyl-pyrimidine-2,4-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,5-Difluorobenzyl bromide | HCID 518896 | — |
| 反応物 | 6-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione | HCID 22256582 | — |
| 生成物 | 1-[(3,5-Difluorophenyl)methyl]-6-(3,5-dimethylbenzoyl)-5-isopropyl-pyrimidine-2,4-dione | HCID 5280014 | 53.3% |
反応手順
5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and 3,5-difluorobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (220 mg, yield: 53.3%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06987114B1 |
| 出典データセット | uspto-grants-2006_01 |
| ORD ID | ord-5314071e3e9e4ec9985da4f9ba04657b |
| 出典メモ | uspto-grants-2006_01 |