Ammonium Hydroxide → beta-Phenyl-L-phenylalanine

HRID 1614697

反応式

HRID 1614697 の反応式
Cl.[C:2]1([CH:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C@@H:9]([C:11]([OH:13])=[O:12])[NH2:10])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[NH4+]>O>[C:2]1([CH:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C@@H:9]([C:11]([OH:13])=[O:12])[NH2:10])[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 14923Ammonium HydroxideHCID 70136519(S)-2-Amino-3,3-diphenylpropanoic acid hydrochloride

生成物 1

HCID 162977beta-Phenyl-L-phenylalanine収率 46%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

D (-)-3,3-Diphenylalanine hydrochloride (0.5 g) is dissolved in 15 mL of water and the pH of the solution is adjusted with dilute ammonium hydroxide solution to pH 7. The precipitate is collected by filtration, washed with water, boiled with water for a short time, cooled to room temperature, and collected to afford 0.2 g of the title compound; mp 218°-220° C. (dec.).

後処理

  1. filtrationThe precipitate is collected by filtration
  2. washwashed with water
  3. customcollected

出典と根拠

ORDレコード
ord-138ffbe38f4746daa81b966f03e18082
出典データセット
uspto-grants-1993_03
特許番号
US05198548

関連ノート

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