Isopropenylacetylene → 2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indole
反応式
I[C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[NH:15][S:16]([CH3:19])(=[O:18])=[O:17].[CH3:20][C:21]([C:23]#[CH:24])=[CH2:22]>>[C:21]([C:23]1[N:15]([S:16]([CH3:19])(=[O:18])=[O:17])[C:3]2[C:2]([CH:24]=1)=[CH:7][C:6]([N+:8]([O-:10])=[O:9])=[C:5]([C:11]([F:14])([F:13])[F:12])[CH:4]=2)([CH3:22])=[CH2:20]参加物
3
実験手順
This compound was prepared using the general Sonagashira conditions as described in general Example C, starting from N-(2-iodo-4-nitro-5-trifluoromethyl-phenyl)-methanesulfonamide (9.0 g, 21.9 mmol) and 2-methyl-1-buten-3-yne (6.25 mL, 65.7 mmol) to yield the title compound as a reddish-brown solid.
後処理
- customThis compound was prepared
出典と根拠
- ORDレコード
- ord-4014a9082c6a4a88ba4e1f405dd17914