Tert-butyl 7-iodo-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate → Tert-butyl 8-iodo-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate
反応式
[I:1]C1C=CC2C3CCN(C(OC(C)(C)C)=O)CC3OC=2C=1.CC1(C)C(C)(C)OB([C:30]2[C:35]3[O:36][CH:37]4[CH:42]([C:34]=3[CH:33]=[CH:32][CH:31]=2)[CH2:41][CH2:40][N:39]([C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44])[CH2:38]4)O1>>[I:1][C:30]1[C:35]2[O:36][CH:37]3[CH:42]([C:34]=2[CH:33]=[CH:32][CH:31]=1)[CH2:41][CH2:40][N:39]([C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44])[CH2:38]3参加物
3
反応物 2
生成物 1
実験手順
Tert-butyl 8-iodo-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate was synthesized as described for tert-butyl 7-iodo-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate P01 starting from tert-butyl 8-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate. MS m/z 402 [M+H]+