Dimethyl Sulfoxide → 1-(7-fluoro-3-methyl-2-pyridin-2-ylquinolin-4-yl)-6-morpholin-4-ylspiro[2H-indole-3,4'-oxane]

反応式

Br[C:2]1[CH:7]=[C:6]2[N:8]([C:16]3[C:25]4[C:20](=[CH:21][C:22]([F:26])=[CH:23][CH:24]=4)[N:19]=[C:18]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=4)[C:17]=3[CH3:33])[CH2:9][C:10]3([CH2:15][CH2:14][O:13][CH2:12][CH2:11]3)[C:5]2=[CH:4][CH:3]=1.[NH:34]1[CH2:39][CH2:38][O:37][CH2:36][CH2:35]1.CS(C)=O.C(=O)([O-])[O-].[K+].[K+]>C(Cl)Cl.O.[Cu]I>[F:26][C:22]1[CH:21]=[C:20]2[C:25]([C:16]([N:8]3[C:6]4[C:5](=[CH:4][CH:3]=[C:2]([N:34]5[CH2:39][CH2:38][O:37][CH2:36][CH2:35]5)[CH:7]=4)[C:10]4([CH2:11][CH2:12][O:13][CH2:14][CH2:15]4)[CH2:9]3)=[C:17]([CH3:33])[C:18]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=3)=[N:19]2)=[CH:24][CH:23]=1