Cesium carbonate → 1-(4-Chloro-5,7-difluoro-3-methylquinolin-2-yl)-5,5-dimethylpiperidin-2-one
反応式
CC1(C)C2C(=C(P(C3C=CC=CC=3)C3C=CC=CC=3)C=CC=2)OC2C(P(C3C=CC=CC=3)C3C=CC=CC=3)=CC=CC1=2.Cl[C:44]1[C:53]([CH3:54])=[C:52]([Cl:55])[C:51]2[C:46](=[CH:47][C:48]([F:57])=[CH:49][C:50]=2[F:56])[N:45]=1.[CH3:58][C:59]1([CH3:66])[CH2:64][NH:63][C:62](=[O:65])[CH2:61][CH2:60]1.C(=O)([O-])[O-].[Cs+].[Cs+]>O1CCOCC1.CCOC(C)=O.C(Cl)Cl.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[Cl:55][C:52]1[C:51]2[C:46](=[CH:47][C:48]([F:57])=[CH:49][C:50]=2[F:56])[N:45]=[C:44]([N:63]2[CH2:64][C:59]([CH3:66])([CH3:58])[CH2:60][CH2:61][C:62]2=[O:65])[C:53]=1[CH3:54]参加物
9
