Dimethyl Sulfoxide → N-[4-[(7-chloroquinolin-4-yl)amino]-2,5-dimethylcyclohexyl]-3,5-difluorobenzamide

HRID 161923

反応式

[CH3:64][S:65]([CH3:66])=[O:67].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([NH:12][CH:13]3[CH:14]([CH3:21])[CH2:15][CH:16]([NH2:20])[CH:17]([CH3:19])[CH2:18]3)[cH:7][cH:8][n:9][c:10]2[cH:11]1.[Cl:22][c:23]1[cH:24][c:25]2[c:26]([c:27]([NH:28][CH:29]3[CH2:30][CH2:31][CH:32]([NH2:33])[CH2:34][CH2:35]3)[cH:36][cH:37][n:38]2)[cH:39][cH:40]1.[F:41][c:42]1[cH:43][c:44]([C:45](=[O:46])[OH:47])[cH:48][c:49]([F:51])[cH:50]1.[nH:52]1[c:53]2[c:54]([cH:55][cH:56][c:57]([C:58]([OH:59])=[O:60])[cH:61]2)[cH:62][cH:63]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([NH:12][CH:13]3[CH:14]([CH3:21])[CH2:15][CH:16]([NH:20][C:45]([c:44]4[cH:43][c:42]([F:41])[cH:50][c:49]([F:51])[cH:48]4)=[O:46])[CH:17]([CH3:19])[CH2:18]3)[cH:7][cH:8][n:9][c:10]2[cH:11]1