(2-Thiophen-2-yl-benzoxazol-6-yl)methanol → 2-Thiophen-2-yl-benzoxazole-6-carbaldehyde

HRID 1619998ノート

反応式

HRID 1619998 の反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][C:8]2[CH:14]=[C:13]([CH2:15][OH:16])[CH:12]=[CH:11][C:9]=2[N:10]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][C:8]2[CH:14]=[C:13]([CH:15]=[O:16])[CH:12]=[CH:11][C:9]=2[N:10]=1

参加物

4

反応物 1

HCID 67466243(2-Thiophen-2-yl-benzoxazol-6-yl)methanol

生成物 1

HCID 820366102-Thiophen-2-yl-benzoxazole-6-carbaldehyde

試薬・触媒・溶媒 2

HCID 178418406HCID 178418406、化合物触媒HCID 6344Dichloromethane溶媒

実験手順

3.7 g (16.0 mmol) (2-thiophen-2-yl-benzoxazol-6-yl)-methanol are dissolved in 200 ml DCM, 15.0 g (10.78 mmol) manganese dioxide are added and the suspension is stirred overnight at RT. The next day the suspension is filtered through kieselguhr and the filtrate is concentrated completely by rotary evaporation i. V.

後処理

  1. filtrationThe next day the suspension is filtered through kieselguhr
  2. concentrationthe filtrate is concentrated completely by rotary evaporation i

出典と根拠

ORDレコード
ord-6b136be23d0844fe8f7d4c78d963c661
出典データセット
uspto-grants-2014_07
特許番号
US08772323B2

反応ノート

読み込み中…