化工社化工社 化学情報印刷レポート · 研究参考用
Tetrahydrofuran → 7-Hydroxychromanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | 3-Hydroxycoumarin | HCID 13650 | — |
| 触媒 | Palladium hydroxide | HCID 9942167 | — |
| 生成物 | 7-Hydroxychromanone | HCID 298130 | — |
反応手順
A solution of hydroxycoumarin (2.0 g, TCI) in anhydrous THF (50 ml) was added with 10% palladium hydroxide/activated carbon (1.0 g, WAKO), and stirred at room temperature for 2 hours under hydrogen atmosphere. The atmosphere was replaced with nitrogen gas, and then the insoluble matters were removed by filtration through Celite. The solvent was evaporated under reduced pressure to obtain the title compound (2.0 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08772327B2 |
| 出典データセット | uspto-grants-2014_07 |
| ORD ID | ord-42b5a6e743ec43ad98e4c4167e7422da |
| 出典メモ | uspto-grants-2014_07 |