Triethylamine → HCID 178484615、化合物
反応式
Cl.[CH3:2][N:3]([CH3:8])[C:4](=[O:7])[CH2:5][NH2:6].C(N(CC)CC)C.S=[C:17]1[CH2:21][S:20][C:19](=[O:22])[NH:18]1>C(O)C>[CH3:2][N:3]([CH3:8])[C:4](=[O:7])[CH2:5][NH:6][C:17]1[CH2:21][S:20][C:19](=[O:22])[N:18]=1参加物
5
実験手順
To a solution of N,N-dimethylglycinamide hydrochloride (5 g) and triethylamine (5.03 mL) in ethanol (20 mL) was added 4-thioxo-1,3-thiazolidin-2-one (4.81 g), and the mixture was stirred at room temperature for 4 hr. The reaction mixture was concentrated, and the residue was purified by silica gel column chromatography (NH, ethyl acetate/THF) to give the title compound (4.68 g).
後処理
- concentrationThe reaction mixture was concentrated
- customthe residue was purified by silica gel column chromatography (NH, ethyl acetate/THF)
出典と根拠
- ORDレコード
- ord-7c043bb9975b4ca5a3935a496f5eff19
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08772277B2
反応ノート
読み込み中…