4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178521297、化合物
反応式
[CH:1]1([NH:4][C:5](=[O:8])[CH2:6][NH2:7])[CH2:3][CH2:2]1.S=[C:10]1[CH2:14][S:13][C:12](=[O:15])[NH:11]1>C(O)C>[CH:1]1([NH:4][C:5](=[O:8])[CH2:6][NH:7][C:10]2[CH2:14][S:13][C:12](=[O:15])[N:11]=2)[CH2:3][CH2:2]1参加物
4
実験手順
To a solution of N-cyclopropylglycinamide (1.22 g) (J. Med. Chem. 2005, 48, 7808-7820) in ethanol (12 mL) was added 4-thioxo-1,3-thiazolidin-2-one (1.42 g), and the mixture was stirred at room temperature for 5 hr. The precipitate was collected by filtration, and the solid was washed with ethanol to give the title compound (2.0 g).
後処理
- filtrationThe precipitate was collected by filtration
- washthe solid was washed with ethanol
出典と根拠
- ORDレコード
- ord-0b8204a8043e4a2d837411209ea78c16
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08772277B2
反応ノート
読み込み中…