4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178518187、化合物
反応式
[NH2:1][C@H:2]1[C@H:7]([OH:8])[CH2:6][CH2:5][O:4][CH2:3]1.S=[C:10]1[CH2:14][S:13][C:12](=[O:15])[NH:11]1>C(O)C>[O:15]=[C:12]1[N:11]=[C:10]([NH:1][C@H:2]2[C@H:7]([OH:8])[CH2:6][CH2:5][O:4][CH2:3]2)[CH2:14][S:13]1参加物
4
実験手順
To a solution of 2-amino-1,5-anhydro-2,4-dideoxy-threo-pentitol (527 mg) in ethanol (100 mL) was added 4-thioxo-1,3-thiazolidin-2-one (590 mg), and the mixture was heated under reflux for 15 hr. The reaction mixture was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (NH, ethyl acetate) to give the title compound (700 mg).
後処理
- temperaturethe mixture was heated
- temperatureunder reflux for 15 hr
- concentrationThe reaction mixture was concentrated under reduced pressure
- customthe residue was purified by silica gel column chromatography (NH, ethyl acetate)
出典と根拠
- ORDレコード
- ord-831048285ab54fbf96293076f12e765d
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08772277B2
反応ノート
読み込み中…