Hexanamide → N,N'-((4-(diethylamino)phenyl)methylene)dihexanamide

HRID 1621192

反応式

HRID 1621192 の反応式
[C:1]([NH2:8])(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH2:9]([N:11]([CH2:20][CH3:21])[C:12]1[CH:19]=[CH:18][C:15]([CH:16]=O)=[CH:14][CH:13]=1)[CH3:10]>>[CH2:9]([N:11]([CH2:20][CH3:21])[C:12]1[CH:19]=[CH:18][C:15]([CH:16]([NH:8][C:1](=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[NH:8][C:1](=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])=[CH:14][CH:13]=1)[CH3:10]

参加物

3

反応物 2

HCID 12332HexanamideHCID 671144-(Diethylamino)benzaldehyde

生成物 1

HCID 71460951N,N'-((4-(diethylamino)phenyl)methylene)dihexanamide収率 76%

実験手順

Compound 53 was prepared from hexanamide and 4-(diethylamino)benzaldehyde using method 1. Yield: 76%. 1H NMR (400 MHz, CD3OD) δ 7.19 (d, J=8.8 Hz, 2H), 6.71 (d, J=8.8 Hz, 2H), 6.58 (t, J=8.4 Hz, 1H), 3.35-3.41 (m, 4H), 2.19-2.26 (m, 4H), 1.61-1.68 (m, 4H), 1.32-1.35 (m, 8H), 1.14 (t, J=6.8 Hz, 6H), 0.94 (t, J=2.8 Hz, 6H). LC-MS (ESI): m/z 390.3 (M+H)+. HRMS (ESI) for C23H40N3O2 (MH+): calcd, 390.3115. found 390.3108.

出典と根拠

ORDレコード
ord-89e4624de9a14678b744ce17a45f567e
出典データセット
uspto-grants-2014_07
特許番号
US08772541B2

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