2-(Trifluoromethyl)thiophene → 5-Bromo-2-chloro-1-(5-trifluoromethyl-2-thienylmethyl)benzene
反応式
[F:1][C:2]([F:9])([F:8])[C:3]1[S:4][CH:5]=[CH:6][CH:7]=1.[Br:10][C:11]1[CH:12]=[CH:13][C:14]([Cl:19])=[C:15]([CH:18]=1)[CH:16]=O>>[Br:10][C:11]1[CH:12]=[CH:13][C:14]([Cl:19])=[C:15]([CH2:16][C:5]2[S:4][C:3]([C:2]([F:9])([F:8])[F:1])=[CH:7][CH:6]=2)[CH:18]=1参加物
3
実験手順
2-Trifluoromethylthiophene (see Japanese Unexamined Patent Publication No. 2000-34239) and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were treated in a manner similar to Reference Example 7 to give the target compound.
後処理
- additionwere treated in a manner similar to Reference Example 7
- customto give the target compound
出典と根拠
- ORDレコード
- ord-c9eb8d722af54ab586ce5fc7712df972
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08785403B2
反応ノート
読み込み中…