4-Bromoanisole → 2-(4-methoxyphenyl)thiophene

反応式

Br[C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][CH:3]=1.[S:10]1[CH:14]=[CH:13][CH:12]=[C:11]1B(O)O>>[CH3:9][O:8][C:5]1[CH:6]=[CH:7][C:2]([C:11]2[S:10][CH:14]=[CH:13][CH:12]=2)=[CH:3][CH:4]=1

参加物

反応物 2

HCID 77304-Bromoanisole

HCID 27339602-Thiopheneboronic acid

生成物 1

HCID 27694252-(4-methoxyphenyl)thiophene

実験手順

p-Bromoanisole and thiophene-2-boronic acid were treated in a manner similar to Reference Example 20-(1) to give 2-(4-methoxyphenyl)thiophene as a pale yellow solid. APCI-Mass m/Z 191 (M+H).

出典と根拠

ORDレコード: ord-fc1e8a457a244078b53087225838df92
出典データセット: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08785403B2

反応ノート

読み込み中…