4-Chloro-1-(2,2-difluoro-ethyl)-1H-pyrazole-3-carboxylic acid methoxy-methyl-amide → 1-(4-Chloro-1-(2,2-difluoroethyl)-1H-pyrazol-3-yl)ethanone
反応式
CON(C)[C:4]([C:6]1[C:10]([Cl:11])=[CH:9][N:8]([CH2:12][CH:13]([F:15])[F:14])[N:7]=1)=[O:5].[CH3:17][Mg]Br>>[Cl:11][C:10]1[C:6]([C:4](=[O:5])[CH3:17])=[N:7][N:8]([CH2:12][CH:13]([F:15])[F:14])[CH:9]=1参加物
3
実験手順
In a manner analogous to that described in Example 14 b), the Grignard reaction of 4-chloro-1-(2,2-difluoro-ethyl)-1H-pyrazole-3-carboxylic acid methoxy-methyl-amide with methylmagnesium bromide yielded the title compound (66% yield) as a colorless oil. MS (ISP): m/z=209.0 [M+H]+.
出典と根拠
- ORDレコード
- ord-e8e9545f6cb5421888d16489d0930898
- 出典データセット
- uspto-grants-2014_07
- 特許番号
- US08785436B2
反応ノート
読み込み中…