化工社化工社 化学情報印刷レポート · 研究参考用
Lumazine → 3-Amino-5,6-dichloropyrazine-2-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Lumazine | HCID 10250 | — |
| 反応物 | Methyl 3-aminopyrazinecarboxylate | HCID 72669 | — |
| 反応物 | Methyl 3-amino-5,6-dichloropyrazine-2-carboxylate | HCID 73828 | — |
| 生成物 | 3-Amino-5,6-dichloropyrazine-2-carbaldehyde | HCID 13367871 | — |
反応手順
The 2-amino-5,6-dichloro-3-(methoxycarbonyl)pyrazine (also named methyl 3-amino-5,6-dichloropyrazinecarboxylate) may be prepared by a method described in J. Med. Chem. 10, 66 (1967), from 2-amino-3-carbomethoxypyrazine, reported in J. Am. Chem. Soc. 67, 1711 (1945), which in turn is prepared from lumazine whose preparation from readily available materials is reported in J. Am. Chem. Soc. 67, 802 (1945).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04479953 |
| 出典データセット | uspto-grants-1984_10 |
| ORD ID | ord-177d836925c84387a85e5eded9c21c13 |
| 出典メモ | uspto-grants-1984_10 |