(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochloride → 5-[(1-Chloro-1-(trifluoromethyl)ethyl]-2-methoxybenzylamino]-2-phenylpiperidine dihydrochloride
反応式
[Cl:1][C:2]([N:8]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[O:28][CH3:29])[CH:9]1[CH2:14][NH:13][CH:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:11][CH2:10]1)([C:4]([F:7])([F:6])[F:5])[CH3:3].[ClH:30].Cl.FC(C1C=CC(OC(F)(F)F)=C(C=1)CN[C@H]1CCCN[C@H]1C1C=CC=CC=1)(F)C>>[ClH:1].[ClH:30].[Cl:1][C:2]([N:8]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[O:28][CH3:29])[CH:9]1[CH2:14][NH:13][CH:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:11][CH2:10]1)([C:4]([F:6])([F:5])[F:7])[CH3:3]参加物
3
反応物 2
生成物 1
実験手順
This compound was prepared from Compound 104 in the same manner of Compound 28.
出典と根拠
- ORDレコード
- ord-3a3c2ddc003e493cbdb06dc10892634c
- 出典データセット
- uspto-grants-2003_01
- 特許番号
- US06506775B1
反応ノート
読み込み中…