N,N-di-n-Butyl-2-benzyloxyacetamide → N,N-di-n-Butyl-2-hydroxyacetamide

HRID 1635077

反応式

HRID 1635077 の反応式
[CH2:1]([N:5]([CH2:17][CH2:18][CH2:19][CH3:20])[C:6](=[O:16])[CH2:7][O:8]CC1C=CC=CC=1)[CH2:2][CH2:3][CH3:4]>C(O)C.[Pd].[C]>[CH2:1]([N:5]([CH2:17][CH2:18][CH2:19][CH3:20])[C:6](=[O:16])[CH2:7][OH:8])[CH2:2][CH2:3][CH3:4]

参加物

4

反応物 1

HCID 18675619N,N-di-n-Butyl-2-benzyloxyacetamide

生成物 1

HCID 11008655N,N-di-n-Butyl-2-hydroxyacetamide収率 111.1%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

4 g of N,N-di-n-butyl-2-benzyloxyacetamide were dissolved in 50 ml of ethanol, and a spatula tip of Pd/carbon was added. The mixture was stirred under a hydrogen atmosphere for 16 hours, and then the catalyst was filtered off and the solvent was distilled off. 3 g of an oil were isolated and were immediately reacted further.

後処理

  1. filtrationthe catalyst was filtered off
  2. distillationthe solvent was distilled off

出典と根拠

ORDレコード
ord-a9fb9dcbd46a4b5199a190bd6340d452
出典データセット
uspto-grants-2003_01
特許番号
US06509341B1

関連ノート

読み込み中…