Tert-butyl (4'-fluoro-3-nitro-[1,1'-biphenyl]-4-YL)carbamate → Tert-butyl (3-amino-4'-fluoro-[1,1'-biphenyl]-4-YL)carbamate
反応式
[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[N+:21]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:15]=[CH:16][C:17]([F:20])=[CH:18][CH:19]=2)=[CH:10][C:9]=1[NH2:21])([CH3:4])([CH3:2])[CH3:3]参加物
3
実験手順
Prepared from (4′-fluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example B12) by catalytic hydrogenation with Raney-Nickel according to the general procedure G (method a). Obtained as a light yellow solid (3.40 g).
出典と根拠
- ORDレコード
- ord-87a4a9c4c9d24bc3bb0ed3daad99b872
- 出典データセット
- uspto-grants-2003_01
- 特許番号
- US06509328B1
反応ノート
読み込み中…