Stannous chloride dihydrate → (3-Amino-4'-cyano-biphenyl-4-yl)-carbamic acid tert.-butyl ester

HRID 1635213ノート

反応式

HRID 1635213 の反応式
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[NH2:22])([CH3:4])([CH3:2])[CH3:3]

参加物

3

反応物 2

HCID 61436Stannous chloride dihydrateHCID 69592863(4'-Cyano-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

生成物 1

HCID 69592808(3-Amino-4'-cyano-biphenyl-4-yl)-carbamic acid tert.-butyl ester

実験手順

Prepared from (4′-cyano-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example C13) by reduction with SnCl2.2H2O according to the general procedure G (method b). Obtained as a yellow solid (360 mg).

出典と根拠

ORDレコード
ord-af4502aacce847409fd68984e6310f19
出典データセット
uspto-grants-2003_01
特許番号
US06509328B1

反応ノート

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