Trifluoroacetic anhydride → 6-(2-Imidazol-1-yl-pyridin-4-yl)-2,2-dimethyl-[1,3]dioxin-4-one
反応式
[C:1]([O:5][C:6](=[O:21])[CH2:7][C:8]([C:10]1[CH:15]=[CH:14][N:13]=[C:12]([N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)[CH:11]=1)=[O:9])(C)([CH3:3])[CH3:2].C(OC(C(F)(F)F)=O)(C(F)(F)F)=O>C(O)(C(F)(F)F)=O.CC(C)=O>[N:16]1([C:12]2[CH:11]=[C:10]([C:8]3[O:9][C:1]([CH3:3])([CH3:2])[O:5][C:6](=[O:21])[CH:7]=3)[CH:15]=[CH:14][N:13]=2)[CH:20]=[CH:19][N:18]=[CH:17]1参加物
4
実験手順
Prepared from 3-(2-imidazol-1-yl-pyridin-4-yl)-3-oxo-propionic acid tert.-butyl ester (Example H5) by stirring in TFA/acetone with TFAA according to general procedure J (method b). Obtained as a brown solid (10.8 g).
出典と根拠
- ORDレコード
- ord-96008cd0283e4b718c0107cc49dec39a
- 出典データセット
- uspto-grants-2003_01
- 特許番号
- US06509328B1
反応ノート
読み込み中…