関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethoxymethane | HCID 8020 | — |
| 反応物 | (Ethylthio)benzene | HCID 12144 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | 1,2-Dichloroethane | HCID 11 | — |
| 生成物 | 4-(Ethylthio)benzyl chloride | HCID 18673858 | — |
反応手順
Aluminum chloride (2 g, 15 mmol) was suspended in 8 mL 1,2-dichloroethane and the solution was cooled to 5° C. Dimethoxymethane (0.69 mL, 7.8 mmol) over 10 min. Ethylphenylsulfide (0.88 mL, 6.5 mmol) was added and the mixture was warmed to rt. After 15 h ice water was added and the mixture was extracted with methylene chloride (3×). The combined organic fractions were dried over magnesium sulfate and concentrated. The crude material was used directly in the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06511994B2 |
|---|
| 出典データセット | uspto-grants-2003_01 |
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| ORD ID | ord-28964c644ded4d8ebef150e94210722b |
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| 出典メモ | uspto-grants-2003_01 |
|---|
