Cinchomeronic acid → 1H,3H-furo(3,4-c)pyridine-1,3-dione

HRID 1636323

反応式

HRID 1636323 の反応式
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([OH:9])=O)=[C:3]([C:10]([OH:12])=[O:11])[CH:2]=1>C(OC(=O)C)(=O)C>[N:1]1[CH:6]=[CH:5][C:4]2[C:7]([O:12][C:10](=[O:11])[C:3]=2[CH:2]=1)=[O:9]

参加物

3

反応物 1

HCID 10273Cinchomeronic acid

生成物 1

HCID 2783981H,3H-furo(3,4-c)pyridine-1,3-dione収率 75.5%

試薬・触媒・溶媒 1

HCID 7918Acetic Anhydride溶媒

実験手順

A mixture of 3,4-pyridine-dicarboxylic acid (15 g) and acetic anhydride (30 ml) is refluxed for 2 hours. The acetic anhydride in excess is distilled off and the residue is purified by sublimation (123° C. at 3 mmHg) to give 10.1 g of 3,4-pyridine-dicarboxylic acid anhydride, a white solid, m.p. 74-76° C.

後処理

  1. temperatureis refluxed for 2 hours
  2. distillationThe acetic anhydride in excess is distilled off
  3. customthe residue is purified by sublimation (123° C. at 3 mmHg)

出典と根拠

ORDレコード
ord-295789ffbf0143ab9a2269b289a48499
出典データセット
uspto-grants-2000_03
特許番号
US06034092

関連ノート

読み込み中…