Water → 6-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one

HRID 1636433

反応式

HRID 1636433 の反応式
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([CH2:12][CH2:13][CH3:14])=[C:7](Cl)[C:6]=2[CH:16]=1.[CH2:17]([N:19]([CH2:23][CH3:24])[C:20](=[S:22])[S-:21])[CH3:18].[Na+].O>CN(C)C=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([CH2:12][CH2:13][CH3:14])=[C:7]([S:22][C:20](=[S:21])[N:19]([CH2:23][CH3:24])[CH2:17][CH3:18])[C:6]=2[CH:16]=1

参加物

5

反応物 3

HCID 962WaterHCID 533728Sodium DiethyldithiocarbamateHCID 193516286-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one

生成物 1

HCID 193516196-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

A solution of 6-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one (0.5 g) in dimethylformamide (2 ml) was treated with sodium diethyldithiocarbamate (0.34 g). The mixture was stirred at room temperature under nitrogen overnight and then poured into water, extracted with diethyl ether and the extract washed with brine, dried and evaporated under reduced pressure to give 6-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one, m.p. 135-7°. (compound 16)

後処理

  1. extractionextracted with diethyl ether
  2. washthe extract washed with brine
  3. customdried
  4. customevaporated under reduced pressure

出典と根拠

ORDレコード
ord-68208a4527674e13946886f99212d572
出典データセット
uspto-grants-2000_03
特許番号
US06034121

関連ノート

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