Carbonochloridic acid, 4-methoxyphenyl ester → 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(4-methoxyphenoxy)carbonyl]hydrazine

HRID 1637388

反応式

HRID 1637388 の反応式
Cl[C:2]([O:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][CH:6]=1)=[O:3].[CH3:13][S:14]([N:17]([CH2:32][CH2:33][Cl:34])[N:18]([S:28]([CH3:31])(=[O:30])=[O:29])C(OC1C=CC=CC=1)=O)(=[O:16])=[O:15]>>[CH3:13][S:14]([N:17]([CH2:32][CH2:33][Cl:34])[N:18]([S:28]([CH3:31])(=[O:30])=[O:29])[C:2]([O:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][CH:6]=1)=[O:3])(=[O:15])=[O:16]

参加物

3

反応物 2

HCID 82128Carbonochloridic acid, 4-methoxyphenyl esterHCID 97995471,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-(phenoxycarbonyl)hydrazine

生成物 1

HCID 99308771,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(4-methoxyphenoxy)carbonyl]hydrazine

実験手順

1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(4-methoxyphenoxy)carbonyl]hydrazine (compound 10g) was prepared by reacting compound 2 with 4-methoxyphenyl chloroformate using a procedure similar to the one employed for compound 10d. The product was recrystallized from ethanol, and the yield was about 30.0% by weight. The Mp of the product was approximately 119-121° C. 1H NMR (CDCl3): δ 7.1 and 6.9 (4H, 2d, aromatic H), 3.6-4.2 (4H, m, CH2CH2Cl), 3.8 (3H, s, OCH3), 3.5 and 3.2 (6H, 2s, 2 CH3SO2).

後処理

  1. customThe product was recrystallized from ethanol
  2. customwas approximately 119-121° C

出典と根拠

ORDレコード
ord-3e48db7a8c6f411bac1006b7d96ff022
出典データセット
uspto-grants-2000_03
特許番号
US06040338

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