化工社化工社 化学情報印刷レポート · 研究参考用
1-Pentanol → 5-Pentyloxy-pyrrolidin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Pentanol | HCID 6276 | — |
| 反応物 | 5-Hydroxy-2-pyrrolidone | HCID 194148 | — |
| 生成物 | 5-Pentyloxy-pyrrolidin-2-one | HCID 15696558 | — |
反応手順
2.5 g of 5-hydroxy-pyrrolidin-2-one and 1.25 g of Amberlite IR 120H are heated to 65° C. for 3 hours in 55 cm3 of 1-pentanol. The resin is filtered off, and the remainder is distilled under reduced pressure at a temperature of 22° C./24° C. under 0.5 mbar. The residue is chromatographed on silica (eluent: ethyl acetate), and 2.68 g of the expected product is obtained. m.p. 42°-43° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04882350 |
| 出典データセット | uspto-grants-1989_11 |
| ORD ID | ord-2da8a7d65e384104a555b0c5607d181e |
| 出典メモ | uspto-grants-1989_11 |