関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 4-Aminobenzonitrile | HCID 13396 | — |
| 反応物 | 2-Amino-4,6-dichloropyrimidine | HCID 65522 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-[(2-Amino-6-chloropyrimidin-4-yl)amino]benzonitrile | HCID 240806 | — |
反応手順
300 mg (1.83 mmol) of 2-amino-4,6-dichloropyrimidine and 216 mg (1.83 mmol) of 4-aminobenzonitrile are suspended in 6 ml of water. 180 μl of concentrated hydrochloric acid are added, and the mixture is stirred at 100° C. overnight. The precipitate is filtered off with suction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07737153B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-b294971d5690468ca48fed2a90495ae2 |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
