Methanol → Benzoic acid, 2,4-dimethoxy-, methyl ester
反応式
S(=O)(=O)(O)O.[CH3:6][O:7][C:8]1[CH:16]=[C:15]([O:17][CH3:18])[CH:14]=[CH:13][C:9]=1[C:10]([OH:12])=[O:11].[CH3:19]O>>[CH3:6][O:7][C:8]1[CH:16]=[C:15]([O:17][CH3:18])[CH:14]=[CH:13][C:9]=1[C:10]([O:12][CH3:19])=[O:11]参加物
4
実験手順
2.1 1 ml of conc. sulfuric acid is added to a solution of 100 g of 2,4-dimethoxybenzoic acid in 500 ml of methanol, and the mixture is refluxed for 14 hours. The mixture is cooled, the solvent is removed, the residue is dissolved in 1 litre of MTB, the solution is washed three times with 200 ml of water each time and dried, and the solvent is removed, giving 105.5 g of methyl 2,4-dimethoxybenzoate.
後処理
- temperaturethe mixture is refluxed for 14 hours
- temperatureThe mixture is cooled
- customthe solvent is removed
- dissolutionthe residue is dissolved in 1 litre of MTB
- washthe solution is washed three times with 200 ml of water each time
- customdried
- customthe solvent is removed
出典と根拠
- ORDレコード
- ord-983bb4facea74c9bb6e67f78732e7afd
- 出典データセット
- uspto-grants-2012_02
- 特許番号
- US08119795B2
反応ノート
読み込み中…