tert-Butyl 6-chloro-1,2,3,4-tetrahydroquinolin-3-ylcarbamate → N-(6-chloro-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

反応式

[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([NH:12]C(=O)OC(C)(C)C)[CH2:5]2.C(C1C=C2C(=CC=1)NC[C@@H](N[S:33]([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)(=[O:35])=[O:34])C2)#N>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([NH:12][S:33]([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)(=[O:35])=[O:34])[CH2:5]2

参加物

反応物 2

HCID 59297067tert-Butyl 6-chloro-1,2,3,4-tetrahydroquinolin-3-ylcarbamate

HCID 66757946(S)-N-(6-Cyano-1,2,3,4-tetrahydro-quinolin-3-yl)-benzenesulfonamide

生成物 1

HCID 59778174N-(6-chloro-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

実験手順

Compound 21B was prepared from 21A by procedures analogous to those described in Example 1D and 1G.

出典と根拠

ORDレコード: ord-15282ee55be74598b0c9e4bfe75f624c
出典データセット: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08119808B2

反応ノート

読み込み中…