Phenylboronic Acid → N-(6-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

反応式

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([NH:12][S:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=[O:15])=[O:14])[CH2:5]2.[C:22]1(B(O)O)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:22]1([C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[NH:8][CH2:7][CH:6]([NH:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)(=[O:15])=[O:14])[CH2:5]3)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

参加物

反応物 2

HCID 66827Phenylboronic Acid

HCID 18177113N-(6-Bromo-1,2,3,4-tetrahydroquinolin-3-yl)-benzenesulfonamide

生成物 1

HCID 17758907N-(6-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

実験手順

Compound 170A was prepared from 87A and phenylboronic acid by procedures analogous to those described in Example 91A.

出典と根拠

ORDレコード: ord-e609acf8a9f54153804ea4129ce7377d
出典データセット: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08119808B2

反応ノート

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