Hydrochloric Acid → 1-[2-(4-Aminopiperidin-1-yl)ethyl]-6,8-difluoroquinoxalin-2(1H)-one
反応式
C(OC(=O)[NH:7][CH:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][N:16]2[C:25]3[C:20](=[CH:21][C:22]([F:27])=[CH:23][C:24]=3[F:26])[N:19]=[CH:18][C:17]2=[O:28])[CH2:10][CH2:9]1)(C)(C)C.Cl.NC1CCN(CCN2C3C(=C(F)C=C(F)C=3)N=CC2=O)CC1>O1CCOCC1>[NH2:7][CH:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][N:16]2[C:25]3[C:20](=[CH:21][C:22]([F:27])=[CH:23][C:24]=3[F:26])[N:19]=[CH:18][C:17]2=[O:28])[CH2:10][CH2:9]1参加物
5
反応物 3
生成物 1
試薬・触媒・溶媒 1
実験手順
tert-Butyl{1-[2-(6,8-difluoro-2-oxoquinoxalin-1(2H)-yl)ethyl]piperidin-4-yl}carbamate (Intermediate 194) was deprotected with HCl in dioxane as described for Intermediate 192.
出典と根拠
- ORDレコード
- ord-487f841c1e8d4556ad4f10c21e39dcdd
- 出典データセット
- uspto-grants-2012_02
- 特許番号
- US08124602B2
反応ノート
読み込み中…