3-(Methoxymethyl)-1-benzofuran-2-carboxylic acid → 3-{4-[(3-Methoxymethyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester
反応式
[CH3:1][O:2][CH2:3][C:4]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[O:6][C:5]=1[C:13]([OH:15])=O.[CH2:16]([O:18][C:19]([N:21]1[CH2:25][CH2:24][CH:23]([O:26][C:27]2[CH:32]=[CH:31][C:30]([NH2:33])=[CH:29][CH:28]=2)[CH2:22]1)=[O:20])[CH3:17]>>[CH2:16]([O:18][C:19]([N:21]1[CH2:25][CH2:24][CH:23]([O:26][C:27]2[CH:28]=[CH:29][C:30]([NH:33][C:13]([C:5]3[O:6][C:7]4[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=4[C:4]=3[CH2:3][O:2][CH3:1])=[O:15])=[CH:31][CH:32]=2)[CH2:22]1)=[O:20])[CH3:17]参加物
3
実験手順
With a procedure similar to the example above, 3-{4-[(3-methoxymethyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester was prepared from 3-methoxymethyl-benzofuran-2-carboxylic acid and 3-(4-amino-phenoxy)-pyrrolidine-1-carboxylic acid ethyl ester. LCMS calcd for C24H26N2O6 (m/e) 438, obsd 439 (M+H).
出典と根拠
- ORDレコード
- ord-05301dd839be4d0891bb96447bd85d5f
- 出典データセット