5-Benzyloxy-2,2-dimethyl-1,3-dioxane → 2-(Phenylmethoxy)-1,3-propanediol

HRID 1645543

反応式

HRID 1645543 の反応式
[CH2:1]([O:8][CH:9]1[CH2:14][O:13]C(C)(C)[O:11][CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO>[CH2:1]([O:8][CH:9]([CH2:10][OH:11])[CH2:14][OH:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

3

反応物 1

HCID 203648895-Benzyloxy-2,2-dimethyl-1,3-dioxane

生成物 1

HCID 2035672-(Phenylmethoxy)-1,3-propanediol収率 94%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a methanol (50 ml) solution of the 5-(benzyloxy)-2,2-dimethyl-1,3-dioxane (6.5 g, 29.2 mmol) obtained in the step (9b), DOWEX(R) 50W-X8 (5 g) was added and stirred at room temperature. After 2 hours, the reaction mixture was filtered and concentrated to obtain the title compound (5.0 g, 93.8%) as a colorless oil.

後処理

  1. additionwas added
  2. filtrationthe reaction mixture was filtered
  3. concentrationconcentrated

出典と根拠

ORDレコード
ord-ca7accb0a7f343e28645d1fab8d4f783
出典データセット
uspto-grants-2012_02
特許番号
US08124780B2

関連ノート

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