HCID 19100958、化合物 → 1-Phenyloctahydropyrrolo[3,4-b]pyrrole
反応式
[C:1]1([N:7]2[CH2:14][CH2:13][CH:12]3[CH:8]2[CH2:9][N:10](C(OCC)=O)[CH2:11]3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>Cl>[C:1]1([N:7]2[CH2:14][CH2:13][CH:12]3[CH:8]2[CH2:9][NH:10][CH2:11]3)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1参加物
3
実験手順
7.6 g (31.6 mmol) of ethyl 2-phenyl-2,7-diazabicyclo[3.3.0]octane-7-carboxylate are heated under reflux overnight with 50 ml of concentrated hydrochloric acid. The mixture is concentrated, the residue is taken up in 50 ml of 10% strength sodium hydroxide solution and the mixture is extracted five times using 50 ml of chloroform each time. The extracts are dried over potassium carbonate and concentrated, and the residue is distilled.
後処理
- concentrationThe mixture is concentrated
- extractionthe mixture is extracted five times
- dry with materialThe extracts are dried over potassium carbonate
- concentrationconcentrated
- distillationthe residue is distilled
出典と根拠
- ORDレコード
- ord-14aaed3fdbde47368b7c4038eea193fb
- 出典データセット
- uspto-grants-1993_01
- 特許番号
- US05177210
反応ノート
読み込み中…