Formic Acid → HCID 19738500、化合物

HRID 1645999ノート

反応式

HRID 1645999 の反応式
[Cl:1][C:2](=[CH2:16])[CH2:3][N:4]([CH2:10][CH:11](OC)[O:12]C)[C:5](=[O:9])[O:6][CH2:7][CH3:8].C(O)=O.[Cl-].[Na+]>O>[Cl:1][C:2](=[CH2:16])[CH2:3][N:4]([CH2:10][CH:11]=[O:12])[C:5](=[O:9])[O:6][CH2:7][CH3:8]

参加物

5

反応物 3

HCID 284Formic AcidHCID 5234Sodium ChlorideHCID 19738531HCID 19738531、化合物

生成物 1

HCID 19738500HCID 19738500、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

151 g (0.6 mol) of ethyl N-(2-chloroallyl)-N-(2,2-dimethoxyethyl)-carbamate are heated under reflux for 3 hours with 60 ml of formic acid in 1.2 1 of water. The mixture is saturated with sodium chloride, and the aqueous phase is separated off and extracted twice with 300 ml of methylene chloride each time. The organic phases are washed with saturated sodium hydrogen carbonate solution until neutral, dried over magnesium sulphate and concentrated, and the residue is distilled.

後処理

  1. customthe aqueous phase is separated off
  2. extractionextracted twice with 300 ml of methylene chloride each time
  3. washThe organic phases are washed with saturated sodium hydrogen carbonate solution until neutral,
  4. dry with materialdried over magnesium sulphate
  5. concentrationconcentrated
  6. distillationthe residue is distilled

出典と根拠

ORDレコード
ord-9f3b9edf736a4634b546dad2b53955a7
出典データセット
uspto-grants-1993_01
特許番号
US05177210

反応ノート

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