Hydrochloric Acid → N-[[2-(Phosphonomethyl)phenyl]methyl]glycine, hydrochloride

HRID 1646179ノート

反応式

HRID 1646179 の反応式
C([O:3][P:4]([CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH2:16][NH:17][CH2:18][C:19]([O:21]C)=[O:20])([O:6]CC)=[O:5])C.[ClH:23]>>[ClH:23].[P:4]([CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH2:16][NH:17][CH2:18][C:19]([OH:21])=[O:20])([OH:6])([OH:5])=[O:3]

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 19801611HCID 19801611、化合物

生成物 1

HCID 85635052N-[[2-(Phosphonomethyl)phenyl]methyl]glycine, hydrochloride

実験手順

A solution of methyl N-[[2[(diethoxyphosphinyl)methyl]phenyl]methyl]glycinate (Example 1) (0.5 g, 1.5 mmol) in 6N hydrochloric acid solution (10 ml) is stirred at reflux in an oil bath for 18 hours. The water is removed in vacuo to give 0.4 g of a white solid.

後処理

  1. temperatureat reflux in an oil bath for 18 hours
  2. customThe water is removed in vacuo

出典と根拠

ORDレコード
ord-3cbc00c8eb004dacb065bb8bafcc3c18
出典データセット
uspto-grants-1993_01
特許番号
US05179085

反応ノート

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