N-methyl-2-pyrrolidone → HCID 15158253、化合物
反応式
CN1CCCC1=O.[CH:8]1[C:20]2[N:19]([NH2:21])[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[C:12]=2[CH:11]=[CH:10][CH:9]=1.[Cl:22][C:23]1[CH:28]=[C:27](Cl)[N:26]=[CH:25][N:24]=1>O>[Cl:22][C:23]1[N:24]=[CH:25][N:26]=[C:27]([NH:21][N:19]2[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[C:12]3[C:20]2=[CH:8][CH:9]=[CH:10][CH:11]=3)[CH:28]=1参加物
5
反応条件
- 温度
- 100 °C
実験手順
To 150 ml of 1-methyl-2-pyrrolidinone was added 10.0 g of 9H-carbazol-9-amine, and 8.2 g of 4,6-dichloropyrimidine, and the mixture was heated to 100° C. and stirred for eleven hours. The mixture was then poured into water and extracted with toluene. The organic layer was washed with water and dried (sat. NaCl, anhydrous MgSO4).