Methanol → 3-(3-Oxo-3-phenyl-1-propenyl)-benzoic acid, methyl ester
反応式
[O:1]=[C:2]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH:3]=[CH:4][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([OH:10])=[O:9].[CH3:20]O>S(=O)(=O)(O)O>[O:1]=[C:2]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH:3]=[CH:4][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([O:10][CH3:20])=[O:9]参加物
4
実験手順
A slurry of 3-(3-oxo-3-phenyl-1-propenyl)-benzoic acid (2.84 g, 11.26 mmol) in methanol (150 mL) is treated with a few drops of sulfuric acid and heated under reflux for 8 hours. Upon cooling, a solid forms which is collected by filtration and washed thoroughly with methanol to provide 0.9 g of the title compound.
後処理
- temperatureheated
- temperatureunder reflux for 8 hours
- temperatureUpon cooling
- filtrationa solid forms which is collected by filtration
- washwashed thoroughly with methanol
出典と根拠
- ORDレコード
- ord-01adc58a6aba4a299f8247ba4ee41c3e
- 出典データセット
- uspto-grants-1995_07
- 特許番号
- US05430047
反応ノート
読み込み中…