Acetic Anhydride → Methyl 2-(methoxymethylidene)-3-oxopentanoate
反応式
[C:1]([CH2:5][C:6]([O:8][CH3:9])=[O:7])(=[O:4])[CH2:2][CH3:3].[CH:10](OC)(OC)[O:11][CH3:12].C(OC(=O)C)(=O)C>>[C:1]([C:5](=[CH:10][O:11][CH3:12])[C:6]([O:8][CH3:9])=[O:7])(=[O:4])[CH2:2][CH3:3]参加物
4
実験手順
A mixture of methyl propionylacetate (112.2 g, 0.86 mol), trimethyl orthoformate (188 ml, 1.72 mol) and acetic anhydride (81 ml, 0.86 mol) was heated at reflux for 17 hours, then the volatile material removed in vacuo, finally at 70°/0.3 mm. The residue was predominantly methyl 2-propanoyl-3-methoxyacrylate, and was used without further purification.
後処理
- temperaturewas heated
- temperatureat reflux for 17 hours
- customthe volatile material removed in vacuo, finally at 70°/0.3 mm
- customwas used without further purification
出典と根拠
- ORDレコード
- ord-2b691a637be1456aae3ff83b60a711a0
- 出典データセット
- uspto-grants-1995_07
- 特許番号
- US05432182
反応ノート
読み込み中…