HCID 178459173、化合物 → HCID 10036866、化合物
反応式
[C:1]([C:5](=[CH:10][NH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18][CH3:19])[C:6]([O:8]C)=O)(=[O:4])[CH2:2][CH3:3]>C1(OC2C=CC=CC=2)C=CC=CC=1>[C:1]([C:5]1[C:6](=[O:8])[C:17]2[C:12](=[C:13]([O:18][CH3:19])[CH:14]=[CH:15][CH:16]=2)[NH:11][CH:10]=1)(=[O:4])[CH2:2][CH3:3]参加物
3
実験手順
Methyl 2-propanoyl-3-(2-methoxyphenylamino)acrylate (77.7 g, 0.29 mol) was added to boiling diphenyl ether (500 ml) then heated at reflux for 1 hour. The solution was partially cooled and poured into high-boiling petroleum ether, then the solid filtered off and washed with 40-60 petroleum ether to give 3-propanoyl-8-methoxy-4(1H)-quinolone (35.6 g, 52%), m.p. 260°-263°
後処理
- temperaturethen heated
- temperatureat reflux for 1 hour
- temperatureThe solution was partially cooled
- filtrationthe solid filtered off
- washwashed with 40-60 petroleum ether
出典と根拠
- ORDレコード
- ord-d0a02e163c984a1f941938ec04f99ff6
- 出典データセット
- uspto-grants-1995_07
- 特許番号
- US05432182
反応ノート
読み込み中…