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Sodium Hydroxide → 9,9-Bis(4-pyridinylmethyl)-2-methylfluorene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 2-Methylfluorene | HCID 15026 | — |
| 反応物 | 4-(Chloromethyl)pyridinium chloride | HCID 74570 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 9,9-Bis(4-pyridinylmethyl)-2-methylfluorene | HCID 14941570 | — |
反応手順
The title compound was prepared following the procedure of Example 5 from 0.95 g of 2-methylfluorene, 2.17 g of 4-picolylchloride hydrochloride, 50 mg of cetyl(Bu)3PBr, 30 ml toluene, and 5 ml 50% NaOH by reaction at 50° for 6 hrs. The material was chromatographed to yield 0.2 g product. NMR (CDCl3, 200 MHz) δ: 2.47(s,3H), 3.37(s,4H), 6.49(d,J=5.3 Hz,4H), 7.03-7.45(arom.H), 8.09(d,4H). HRMS calculated for C26H22N2 : 362.1783 Found: 362.1778
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05434264 |
| 出典データセット | uspto-grants-1995_07 |
| ORD ID | ord-37333062a4d341f784328f46ee2b1616 |
| 出典メモ | uspto-grants-1995_07 |