Diphenylcyclopropenone → HCID 21462217、化合物

HRID 1648159ノート

反応式

HRID 1648159 の反応式
[C:1]1([C:7]2[C:9](=[O:10])[C:8]=2[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17]([C:19]1[CH:20]=[N:21][CH:22]=[CH:23][C:24]=1[C:25]#[N:26])#[N:18]>ClC1C=CC=CC=1>[OH:10][C:9]1[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[C:8]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[N:21]2[C:22]=1[CH:23]=[C:24]([C:25]#[N:26])[C:19]([C:17]#[N:18])=[CH:20]2

参加物

4

反応物 2

HCID 65057DiphenylcyclopropenoneHCID 74211Pyridine-3,4-dicarbonitrile

生成物 1

HCID 21462217HCID 21462217、化合物

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

Diphenylcyclopropenone (0.319 g, 1.55 mmol) and 3,4-dicyanopyridine (0.200 g, 1.55 mmol) were mixed in a dry, argon filled reaction flask. Chlorobenzene (2.5 mL) (oxygen free) was added, and the reaction was heated to 130C. After 2 h the heating was stopped and the reaction was allowed to reach room temperature. Petroleum ether 40-60C (2.5 mL) was added in order to obtain a complete precipitate of the product. The solvent was filtered off and the precipitate was washed with petroleum ether. The crude product was stirred with chloroform (30. mL) for lb. The dark chloroform solution was filtered off leaving the title product as a yellow precipitate.

後処理

  1. additionfilled
  2. customreaction flask
  3. customto reach room temperature
  4. customto obtain a complete precipitate of the product
  5. filtrationThe solvent was filtered off
  6. washthe precipitate was washed with petroleum ether
  7. filtrationThe dark chloroform solution was filtered off

出典と根拠

ORDレコード
ord-2bd5c21322c742cfb57ecb786c08207f
出典データセット
uspto-grants-1995_07
特許番号
US05435991

反応ノート

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