2,2,6-Trimethyl-5-phenyl-2H,4H-1,3-dioxin-4-one → 3-[1-(3-chlorophenyl)cyclopentyl]-6-methyl-5-phenyl-2,3-dihydro-4H-1,3-oxazin-4-one
反応式
[C:1]1([C:7]2[C:8](=[O:16])O[C:10](C)(C)[O:11][C:12]=2[CH3:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C=[N:18][C:19]1([C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([Cl:30])[CH:25]=2)[CH2:23][CH2:22][CH2:21][CH2:20]1>C1(C)C(C)=CC=CC=1>[Cl:30][C:26]1[CH:25]=[C:24]([C:19]2([N:18]3[C:8](=[O:16])[C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)=[C:12]([CH3:13])[O:11][CH2:10]3)[CH2:23][CH2:22][CH2:21][CH2:20]2)[CH:29]=[CH:28][CH:27]=1参加物
4
実験手順
A mixture of 5-phenyl-2,2,6-trimethyl-2H,4H-1,3-dioxin-4-one (0.65 g) and N-methylene-1-(3-chlorophenyl)cyclopentylamine (0.78 g) and xylene (3 ml) was heated at reflux for 30 minutes for reaction. The reaction mixture was purified by silica gel chromatography to obtain the captioned compound (0.97 g).