2,2,6-Trimethyl-5-phenyl-2H,4H-1,3-dioxin-4-one → 3-(1,1-dimethyl-2-phenylethyl)6-methyl-5-phenyl-2,3-dihydro-4H-1,3-oxazin-4-one

HRID 1648197ノート

反応式

HRID 1648197 の反応式
[C:1]1([C:7]2[C:8](=[O:16])O[C:10](C)(C)[O:11][C:12]=2[CH3:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C=[N:18][C:19]([CH3:28])([CH3:27])[CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH3:28][C:19]([N:18]1[C:8](=[O:16])[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[C:12]([CH3:13])[O:11][CH2:10]1)([CH3:27])[CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

参加物

3

反応物 2

HCID 131570242,2,6-Trimethyl-5-phenyl-2H,4H-1,3-dioxin-4-oneHCID 15568651N-methylene-1,1-dimethyl-2-phenylethylamine

生成物 1

HCID 199189533-(1,1-dimethyl-2-phenylethyl)6-methyl-5-phenyl-2,3-dihydro-4H-1,3-oxazin-4-one収率 77.3%

実験手順

5-phenyl-2,2,6-trimethyl-2H,4H-1,3-dioxin-4-one (0.65 g) and N-methylene-1,1-dimethyl-2-phenylethylamine (0.63 g) were reacted at 140° for 30 minutes. The reaction mixture was purified by silica gel chromatography to obtain the captioned compound (0.74 g).

後処理

  1. customThe reaction mixture was purified by silica gel chromatography

出典と根拠

ORDレコード
ord-6c544c79a5cd4a3e8b40b8803ab0139b
出典データセット
uspto-grants-1995_07
特許番号
US05436224

反応ノート

読み込み中…