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HRID 1648394作成日：2026年10月27日

1-(1H-indol-3-yl)-2-methylpropan-2-amine → [2-(1H-indol-3-yl)-1,1-dimethylethyl][2-(2-methyloxyphenoxy)ethyl]amine hydrochloride

https://huagongshe.com/reaction/1648394

反応式

関与物質

役割名称HCID仕込み量
反応物1-(1H-indol-3-yl)-2-methylpropan-2-amineHCID 9353—
反応物Indole, 5-chloro-3-(2-amino-1,1-dimethylethyl)-HCID 26712—
反応物2-(2-Methoxyphenoxy)ethyl methanesulfonateHCID 15289993—
生成物[2-(1H-indol-3-yl)-1,1-dimethylethyl][2-(2-methyloxyphenoxy)ethyl]amine hydrochlorideHCID 67809420—

反応手順

Proceeding as in Example 3, but replacing 2-[2-(cyclopropylmethyloxy)phenoxy]ethyl methanesulfonate with 2-(2-methyloxyphenoxy)ethyl methanesulfonate and [1-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2-(1H-indol-3-yl)-1,1-dimethylethyl]amine, gave [2-(1H-indol-3-yl)-1,1-dimethylethyl][2- (2-methyloxyphenoxy)ethyl]amine hydrochloride, m.p. 156°-158° C.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05436264
出典データセットuspto-grants-1995_07
ORD IDord-71ae478e4b684e1f90f4d101d1cf7a1f
出典メモuspto-grants-1995_07