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5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine → [3-(1H-indol-3-yl)prop-1-yl][2-(2-ethyloxyphenoxy)ethyl]amine hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine | HCID 13260 | — |
| 反応物 | 1H-indole-3-propylamine | HCID 28989 | — |
| 反応物 | 2-(2-Ethoxyphenoxy)ethyl methanesulfonate | HCID 15289994 | — |
| 生成物 | [3-(1H-indol-3-yl)prop-1-yl][2-(2-ethyloxyphenoxy)ethyl]amine hydrochloride | HCID 19919952 | — |
反応手順
Proceeding as in Example 3, but replacing 2-[2-(cyclopropylmethyloxy)phenoxy]ethyl methanesulfonate with 2-(2-ethyloxyphenoxy)ethyl methanesulfonate and [2-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [3-(1H-indol-3-yl)-prop-1-yl]amine, gave [3-(1H-indol-3-yl)prop-1-yl][2-(2-ethyloxyphenoxy)ethyl]amine hydrochloride, m.p. 147°-148° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05436264 |
| 出典データセット | uspto-grants-1995_07 |
| ORD ID | ord-e97df20836744e7795878f1082b43d68 |
| 出典メモ | uspto-grants-1995_07 |