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1-(1H-indol-3-yl)-2-methylpropan-2-amine → [2-(1H-indol-3-yl)-1,1-dimethylethyl]{2-[2-(prop-2-yloxy)phenoxy]ethyl}amine hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(1H-indol-3-yl)-2-methylpropan-2-amine | HCID 9353 | — |
| 反応物 | 5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine | HCID 13260 | — |
| 反応物 | 2-[2-(Prop-2-yloxy)phenoxy]ethyl methanesulfonate | HCID 15289995 | — |
| 生成物 | [2-(1H-indol-3-yl)-1,1-dimethylethyl]{2-[2-(prop-2-yloxy)phenoxy]ethyl}amine hydrochloride | HCID 67809332 | — |
反応手順
Proceeding as in Example 3, but replacing 2-(cyclopropylmethyloxy)phenoxyethyl methanesulfonate with 2-[2-(prop-2-yloxy)phenoxy]ethyl methanesulfonate and [2- (5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2-(1H-indol-3-yl)-1,1-dimethylethyl]amine, gave [2-(1H-indol-3-yl)-1,1-dimethylethyl]{2- [2-(prop-2-yloxy)phenoxy]ethyl}amine hydrochloride, m.p. 164°-166° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05436264 |
| 出典データセット | uspto-grants-1995_07 |
| ORD ID | ord-7f2a32e666614368bca28aab58404ddd |
| 出典メモ | uspto-grants-1995_07 |